| Away | Home | Projection | Line | Over Win % | Under Win % | |
| Baltimore | @ | Boston | 5.62 | 4.5 | 65.0% | 35.0% |
| Chi Cubs | @ | Cincinnati | 4.11 | 4.0 | 51.5% | 48.5% |
| Milwaukee | @ | Pittsburgh | 3.80 | 3.5 | 54.2% | 45.8% |
| SF Giants | @ | Washington | 4.75 | 4.0 | 60.2% | 39.8% |
| Toronto | @ | Tampa Bay | 4.02 | 5.0 | 36.8% | 63.2% |
| Cleveland | @ | Detroit | 5.80 | 4.5 | 67.2% | 32.8% |
| LA Dodgers | @ | NY Mets | 4.74 | 5.0 | 46.5% | 53.5% |
| Baltimore | @ | Boston | 4.64 | 5.5 | 38.4% | 61.6% |
| San Diego | @ | Atlanta | 4.29 | 4.0 | 54.0% | 46.0% |
| Texas | @ | Chi Sox | 4.64 | 4.0 | 58.7% | 41.3% |
| Seattle | @ | Houston | 6.30 | 5.0 | 67.2% | 32.8% |
| Kansas City | @ | Minnesota | 4.58 | 4.0 | 57.9% | 42.1% |
| Arizona | @ | St. Louis | 5.85 | 4.5 | 67.9% | 32.1% |
| NY Yankees | @ | Colorado | 6.61 | 6.0 | 58.4% | 41.6% |
| Miami | @ | LA Angels | 4.98 | 4.0 | 63.2% | 36.8% |
| Philadelphia | @ | Sacramento | 4.77 | 5.0 | 46.9% | 53.1% |